By Abraham Lieberman
A patient-oriented advisor to dealing with Parkinson disorder and the actual and emotional problems linked to the sickness.
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Extra info for 100 Questions & Answers About Parkinson Disease
Louis, a study compared the features of PD in 15 career welders, to control groups with PD. 4 years). Welders had a younger age at onset (46 years) of PD compared with controls (63 years). There was no difference in frequency of tremor, slowness of movement, rigidity, postural instability, family history, clinical depression, or dementia. All treated welders responded to levodopa. Motor fluctuations and dyskinesias occurred at a similar frequency in welders and the control groups. PET scans with 6-fluorodopa obtained in 2 of the welders showed findings typical of PD.
Alcohol is less beneficial in PD. The affects of alcohol on ET are not well understood, and the overuse of alcohol could, of course, lead to dependence. In general, the drugs for PD do not help ET. ET responds to drugs such as mysoline (a drug used to treat epilepsy), 40 l eb02 11/13/02 1 0 0 11:20 AM Q & A Page 41 A B O U T P A R K I N S O N D I S E A S E inderal (a drug used to treat high blood pressure), and benzodiazepines (drugs used to treat anxiety). Anxiety increases the tremor of ET and PD.
In 1967, before levodopa, Mirapex, Requip, Permax, or Comtan became available, people diagnosed with PD lived, on average, 5 to 15 years from diagnosis to death. Death came in several ways. 18 l eb01 11/13/02 1 0 0 11:15 AM Q & A Page 19 A B O U T P A R K I N S O N D I S E A S E Some Basic Questions 1. People with PD became immobile and were confined to bed 5 to 15 years after diagnosis. Some developed difficulty swallowing. They gagged or choked on their food, even when fed carefully. The food was aspirated or swallowed into the lungs, causing pneumonia.