Download e-book for iPad: Clavis Patrum Latinorum by Eligius Dekkers - Aemilius Gaar

By Eligius Dekkers - Aemilius Gaar

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Inhibition by ethacrynic acid of NO-mediated relaxations of the rat anococcygeus muscle. Clin Exp Pharmacol Physiol 1994;21:293–299. 147. Rapoport RM, Murad F. Effects of ethacrynic acid and cystamine on sodium nitroprusside-induced relaxation, cyclic GMP levels and guanylate cyclase activity in rat aorta. Gen Pharmacol 1988;19:61–65. 148. , Vavrin Z, Taintor RR. L-arginine is required for expression of the activated macrophage effector mechanism causing selective metabolic inhibition in target cells.

Recent experimental and clinical research solved some of the controversies surrounding the myocardial contractile effects of NO. These controversies were: (1) does NO exert a contractile effect at baseline? (2) is NO a positive or a negative inotrope? (3) Are the contractile effects of NO similar when NO is derived from NO-donors or from the different isoforms of NO synthases (NOS)? (4) Does NO exert the same effects in hypertrophied, failing or ischemic myocardium? Transgenic mice with cardioselective overexpression of NOS revealed NO to produce a small reduction in basal developed LV pressure and a LV relaxation-hastening effect mainly through myofilamentary desensitization.

Pharmacol Toxicol 1998;83:44–46. 24. Pino RZ, Feelisch M. ) and nitroxyl using L-cysteine. Biochem Biophys Res Commun 1994;201:54–62. 25. Zamora R, Grzesiok A, Weber H, Feelisch M. Oxidative release of nitric oxide accounts for guanylyl cyclase stimulating, vasodilator and anti-platelet activity of Piloty’s NO in the Vasculature 26. 27. 28. 29. 30. 31. 32. 33. 34. 35. 36. 37. 38. 39. 40. acid: A comparison with Angeli’s salt. Biochem J 1995;312 (Pt 2):333–339. Doyle MP, Mahapatro SN, Broene RD, Guy JK.

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